Différences entre versions de « Coagulation intravasculaire disséminée (CIVD) »
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== Etiologie<ref>Br J Haematol 2009;145:24</ref> == | == Etiologie<ref>Br J Haematol 2009;145:24</ref> == | ||
| − | * Sepsis and severe infection | + | * '''Sepsis and severe infection''' e.g. meningococcemia |
| − | + | * '''Trauma''' e.g. severe head injury | |
| − | * | + | * '''Organ destruction''' e.g. pancreatitis, brain injury, burns |
| − | + | * '''Malignancy''' solid tumors, promyelocytic leukaemia | |
| − | * solid tumors, promyelocytic leukaemia Obstetric complications | + | * '''Obstetric complications''' amniotic fluid embolism, placental abruption, pre-eclampsia |
| − | + | * '''Vascular abnormalities:''' large haemangiomata, vascular aneurysm | |
| − | + | * '''Severe liver failure''' | |
| − | * Toxic insults | + | * '''Toxic insults:''' snake bite, recreational drugs |
| − | + | * '''Immunological insults:''' ABO transfusion incompatibility, transplant rejection | |
| − | * Immunological insults | + | * '''Purpura fulminans''' |
| − | |||
| − | * Purpura fulminans | ||
== Diagnostic == | == Diagnostic == | ||
Version du 10 avril 2020 à 11:33
Etiologie[1]
- Sepsis and severe infection e.g. meningococcemia
- Trauma e.g. severe head injury
- Organ destruction e.g. pancreatitis, brain injury, burns
- Malignancy solid tumors, promyelocytic leukaemia
- Obstetric complications amniotic fluid embolism, placental abruption, pre-eclampsia
- Vascular abnormalities: large haemangiomata, vascular aneurysm
- Severe liver failure
- Toxic insults: snake bite, recreational drugs
- Immunological insults: ABO transfusion incompatibility, transplant rejection
- Purpura fulminans
Diagnostic
- Clinique et
- Biologique
| Paramètre[2] | Valeur | Points |
|---|---|---|
| Thrombocytes | =< 100 G/l | 1 |
| =< 50 G/l | 2 | |
| TP | < 60% | 1 |
| < 45% | 2 | |
| Fibrinogène | =< 1 g/l | 1 |
| Marqueurs de la fibrinolyse | > 1000 ng/ml | 2 |
| > 4000 ng/ml | 3 |
- Critères ISTH pour CIVD: https://www.mdcalc.com/isth-criteria-disseminated-intravascular-coagulation-dic
