Dyslipidémie

Dépistage

Recommandé chez tous les adultes entre 40 et 75 ans^[1]

Diagnostic différentiel

Hypothyroïdie
Diabète non contrôlé
Syndrome néphrotique
Médicaments: glucocorticoïdes, diurétiques, amiodarone

Stratification du risque cardiovasculaire

Calcul: https://www.agla.ch/fr/calculateurs-outils/calculateur-de-risque-du-gsla

Prévention primaire

Sans calcul du score de risque au préalable:^[2]

Adults of any age with an LDL cholesterol level of 4.92 mmol/L or higher should be started on high-intensity statin therapy
Adults aged 40 to 75 years with diabetes should be started on moderate-intensity statin therapy.

Prévention secondaire

Chez les patients suivants:

Syndrome coronarien aigu
Antécédent d'infarctus du myocarde
Angor stable et instable
Antécédent de revascularisation artérielle (coronarienne ou autre)
Antécédent d'AVC ou AIT
AOMI
Anévrisme aortique

High-intensity statin therapy should be initiated in patients with ASCVD who are aged 75 years or younger to achieve a reduction in LDL cholesterol of 50% or greater. If high-intensity statin therapy is contraindicated or not tolerated, moderate-intensity statin therapy should be initiated to achieve a reduction in LDL cholesterol of 30% to 49%.

Références

↑ The U.S. Preventive Services Task Force (USPSTF) recommends universal lipid screening in adults aged 40 to 75 years to calculate risk for atherosclerotic cardiovascular disease (ASCVD) using the American Heart Association (AHA)/American College of Cardiology (ACC) Pooled Cohort Equations
↑ https://mksap18.acponline.org/app/topics/gm/mk18_b_gm_s9/mk18_b_gm_s9_2_2

[1] The U.S. Preventive Services Task Force (USPSTF) recommends universal lipid screening in adults aged 40 to 75 years to calculate risk for atherosclerotic cardiovascular disease (ASCVD) using the American Heart Association (AHA)/American College of Cardiology (ACC) Pooled Cohort Equations

[2] ttps://mksap18.acponline.org/app/topics/gm/mk18_b_gm_s9/mk18_b_gm_s9_2_2

[1]

[2]