Différences entre versions de « Gammapathies monoclonales »
De médecine.top
(→POEMS) |
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| Ligne 10 : | Ligne 10 : | ||
* Souvent lambda | * Souvent lambda | ||
== POEMS == | == POEMS == | ||
| + | (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) | ||
* Souvent IgG/IgA et lambda | * Souvent IgG/IgA et lambda | ||
| − | + | * POEMS syndrome is characterized by the presence of a monoclonal plasma cell disorder, peripheral neuropathy, and one or more of the following: osteosclerotic myeloma, Castleman disease (angiofollicular lymph node hyperplasia), elevated serum vascular endothelial growth factor, organomegaly, endocrinopathy, edema, typical skin changes, and papilledema. | |
[[Category:Hématologie]] | [[Category:Hématologie]] | ||
[[Category:Oncologie]] | [[Category:Oncologie]] | ||
Version du 18 mai 2020 à 17:09
Caractéristiques communes
Neuropathies associated with monoclonal proteins occur in monoclonal gammopathy of undetermined significance, multiple myeloma, Waldenström macroglobulinemia, amyloidosis, and other hematologic malignancies.
MGUS
Hémopathies malignes
IgG: myélome-plasmocytome
IgM: syndrome lymphoprolifératif (lymphome malin)
- Leucémie lymphoïde chronique
- Maladie de Waldenström (lymphome lymphoplasmocytaire)
Amyloïdose
- Souvent lambda
POEMS
(polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes)
- Souvent IgG/IgA et lambda
- POEMS syndrome is characterized by the presence of a monoclonal plasma cell disorder, peripheral neuropathy, and one or more of the following: osteosclerotic myeloma, Castleman disease (angiofollicular lymph node hyperplasia), elevated serum vascular endothelial growth factor, organomegaly, endocrinopathy, edema, typical skin changes, and papilledema.
