Différences entre versions de « Gammapathies monoclonales »
De médecine.top
| Ligne 2 : | Ligne 2 : | ||
Neuropathies associated with monoclonal proteins occur in monoclonal gammopathy of undetermined significance, multiple myeloma, Waldenström macroglobulinemia, amyloidosis, and other hematologic malignancies. | Neuropathies associated with monoclonal proteins occur in monoclonal gammopathy of undetermined significance, multiple myeloma, Waldenström macroglobulinemia, amyloidosis, and other hematologic malignancies. | ||
== Bilan étiologique == | == Bilan étiologique == | ||
| + | {| class="wikitable" | ||
| + | |- | ||
| + | ! Paramètre || Valeur || Signification | ||
| + | |- | ||
| + | | Hyperthyroïdie||Explication ici||Dosage de la '''TSH''' | ||
| + | |- | ||
| + | | Alcool ("holiday heart")||Explication ici|| | ||
| + | |- | ||
| + | | Péricardite||Explication ici||'''ECG''', '''labo''', '''échocardiographie''' | ||
| + | |- | ||
| + | | Embolie pulmonaire||Explication ici||Dosage des '''D-dimères''', '''Angio-CT''' | ||
| + | |||
| + | |} | ||
| + | |||
== MGUS == | == MGUS == | ||
== Hémopathies malignes == | == Hémopathies malignes == | ||
Version du 24 mai 2020 à 12:16
Caractéristiques communes
Neuropathies associated with monoclonal proteins occur in monoclonal gammopathy of undetermined significance, multiple myeloma, Waldenström macroglobulinemia, amyloidosis, and other hematologic malignancies.
Bilan étiologique
| Paramètre | Valeur | Signification |
|---|---|---|
| Hyperthyroïdie | Explication ici | Dosage de la TSH |
| Alcool ("holiday heart") | Explication ici | |
| Péricardite | Explication ici | ECG, labo, échocardiographie |
| Embolie pulmonaire | Explication ici | Dosage des D-dimères, Angio-CT |
MGUS
Hémopathies malignes
IgG: myélome-plasmocytome
IgM: syndrome lymphoprolifératif (lymphome malin)
- Leucémie lymphoïde chronique
- Maladie de Waldenström (lymphome lymphoplasmocytaire)
Amyloïdose
- Souvent lambda
POEMS
(polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes)
- Souvent IgG/IgA et lambda
- POEMS syndrome is characterized by the presence of a monoclonal plasma cell disorder, peripheral neuropathy, and one or more of the following: osteosclerotic myeloma, Castleman disease (angiofollicular lymph node hyperplasia), elevated serum vascular endothelial growth factor, organomegaly, endocrinopathy, edema, typical skin changes, and papilledema.
