Intoxication au monoxyde de carbone

De mé

Cited indications for hyperbaric oxygen therapy include loss of consciousness, ischemic cardiac changes, neurological deficits, significant metabolic acidosis, or carboxyhemoglobin level greater than 25%. A carboxyhemoglobin level of 50% is critical and needs to be reduced as quickly as possible. Breathing 100% oxygen at normal atmospheric pressure, this patient will clear the carboxyhemoglobin with a half-life of 90 minutes, but hyperbaric oxygen therapy will lower the half-life to 30 minutes. Also, there is considerable risk of delayed neurocognitive impairment following a severe exposure such as this, and hyperbaric oxygen is believed to lower the risk of this long-term complication, although the strength of this evidence is disputed.[1]


  • Carboxyhémoglobinémie normale: <3%
  • Carboxyhémoglobinémie chez les fumeurs: 10%-15%


  • Patients with high levels of carboxyhemoglobin (25% and greater) and evidence of organ ischemia should be treated with hyperbaric oxygen if possible.
  • Methylene blue would be recommended for toxic levels of methemoglobin, usually 20% to 30% or higher.