Différences entre versions de « Intoxication au monoxyde de carbone »
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Cited indications for hyperbaric oxygen therapy include loss of consciousness, ischemic cardiac changes, neurological deficits, significant metabolic acidosis, or carboxyhemoglobin level greater than 25%. A carboxyhemoglobin level of 50% is critical and needs to be reduced as quickly as possible. Breathing 100% oxygen at normal atmospheric pressure, this patient will clear the carboxyhemoglobin with a half-life of 90 minutes, but hyperbaric oxygen therapy will lower the half-life to 30 minutes. Also, there is considerable risk of delayed neurocognitive impairment following a severe exposure such as this, and hyperbaric oxygen is believed to lower the risk of this long-term complication, although the strength of this evidence is disputed.<ref>https://mksap18.acponline.org/app/topics/pm/mk18_b_pm_s13/mk18_b_pm_s13_7_2</ref> | Cited indications for hyperbaric oxygen therapy include loss of consciousness, ischemic cardiac changes, neurological deficits, significant metabolic acidosis, or carboxyhemoglobin level greater than 25%. A carboxyhemoglobin level of 50% is critical and needs to be reduced as quickly as possible. Breathing 100% oxygen at normal atmospheric pressure, this patient will clear the carboxyhemoglobin with a half-life of 90 minutes, but hyperbaric oxygen therapy will lower the half-life to 30 minutes. Also, there is considerable risk of delayed neurocognitive impairment following a severe exposure such as this, and hyperbaric oxygen is believed to lower the risk of this long-term complication, although the strength of this evidence is disputed.<ref>https://mksap18.acponline.org/app/topics/pm/mk18_b_pm_s13/mk18_b_pm_s13_7_2</ref> | ||
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| + | == Traitement == | ||
| + | Methylene blue would be recommended for toxic levels of methemoglobin, usually 20% to 30% or higher<ref> | ||
== Références == | == Références == | ||
[[Category:Médecine d'urgence]] | [[Category:Médecine d'urgence]] | ||
| + | [[Category:Toxicologie]] | ||
Version du 11 février 2020 à 14:30
Cited indications for hyperbaric oxygen therapy include loss of consciousness, ischemic cardiac changes, neurological deficits, significant metabolic acidosis, or carboxyhemoglobin level greater than 25%. A carboxyhemoglobin level of 50% is critical and needs to be reduced as quickly as possible. Breathing 100% oxygen at normal atmospheric pressure, this patient will clear the carboxyhemoglobin with a half-life of 90 minutes, but hyperbaric oxygen therapy will lower the half-life to 30 minutes. Also, there is considerable risk of delayed neurocognitive impairment following a severe exposure such as this, and hyperbaric oxygen is believed to lower the risk of this long-term complication, although the strength of this evidence is disputed.[1]
Traitement
Methylene blue would be recommended for toxic levels of methemoglobin, usually 20% to 30% or higher<ref>
